Results 61-80 of about 167|
  1. ... Info/History Metrics Data Supplements Preview PDF Abstract CRISPR-based genome editing is an enabling technology with ... this technology. A novel Type V, Class 2 CRISPR nuclease system was identified from Microgenomates and Smithella ...
  2. ... investigated the in vivo function of Fank1. Methods. In this study, we generated Fank1-knockout mice using the CRISPR/Cas9 system. We then investigated the phenotype and in vivo function of Fank1. Testes and epididymis tissues ...
    Date: 1969-12-31T19:00:18-0500
  3. Subject: Earth Sciences, Environmental Sciences; land surface modelling; data assimilation; leaf area index; surface soil moisture; summer 2018
  4. Both targeted traps (tm1a) and null (tm1b and CRISPR induced deletions) alleles are employed ... insertion allele, compared with 20 containing exon deletions (19 tm1b and 1 CRISPR). With either group ...
  5. such as the CRISPR-Cas gene editing technology, may encourage some to “play God” due to their supposed capability ...
  6. ... RNA interference, or complete gene knockout, using new CRISPR techniques. These screens can reveal the basic blueprint ... framework for understanding the capabilities and limitations of CRISPR technology, we derive gold-standard reference sets of ...
  7. ... allows to design complex graph editing algorithms. As an example, we developed a detection algorithm for CRISPRs in a de Bruijn graph. Finally, RGFA can be used for comparing assembly graphs, e.g. to document the changes ...
    Date: 1969-12-31T19:00:22-0500
  8. Subject: Social Sciences, Finance; Quinoxaline Analogs, Synthesis, Thymidine phosphorylase inhibition, Molecular docking
  9. and thus generally represent a particularly amenable tool for CRISPR-Cas9 mediated genome editing ...
  10. siRNA small interfering RNA, CRISPR clustered regularly interspaced short palindromic repeats, shRNA ...
  11. ... X-chromosome target sequences for X-shredding by CRISPR endonucleases View ORCID Profile Philippos Aris Papathanos , View ... Info/History Metrics Data Supplements Preview PDF Abstract CRISPR-based synthetic sex ratio distorters, that operate by ...
  12. ... valid cellular model to study the disease, MUT gene was knocked out (KO) in HEK293 cell line by using CRISPR-CAS9 technology. Methylmalonic acid was measured in MUT-KO and wild type (WT) cells by multiple reaction ...
    Date: 1969-12-31T19:00:09-0500
  13. Subject: Physical Sciences, Astronomy & Astrophysics; quantum gravity; vacuum polarization; gravitational dipole; Majorana particle
  14. 2013). Furthermore, a recent genome-wide CRISPR/Cas9 screen indicated a relatively minor contribution ...
  15. palindromic repeat (CRISPR)/Cas-based RNA-guided DNA endonucleases21. TALEN and CRISPR/Cas are based on DNA ...
  16. ... PDF Abstract Clustered regularly interspaced short palindromic repeat (CRISPR) RNA-guided nucleases have gathered considerable excitement as ... we use ChIP-seq to examine genome-wide CRISPR binding specificity at gRNA-specific and gRNA-independent ...
  17. ... responsible manner, a new way of adding new functions into organisms through genome editing. For example, CRISPR/Cas9 genome editing holds enormous potential for providing life saving gene editing capability in medical ...
    Date: 1969-12-31T19:00:12-0500
first · previous · 1 · 2 · 3 · 4 · 5 · 6 · 7 · 8 · next · last