Results 1-6 of 6 in Mice, Mutant
  1. the mutation on the NOD background was created using CRISPR/CAS9 whereas the 3 strains where the KO ... used CRISPR to target the Zbtb32 gene for deletion directly in NOD mice and characterized the mutant ... NOD mice, we introduced a targeted deletion using CRISPR/CAS9 techniques. The creation of mutant NOD ...
  2. ... investigated the in vivo function of Fank1. Methods. In this study, we generated Fank1-knockout mice using the CRISPR/Cas9 system. We then investigated the phenotype and in vivo function of Fank1. Testes and epididymis tissues ...
    Date: 1969-12-31T19:00:18-0500
  3. Both targeted traps (tm1a) and null (tm1b and CRISPR induced deletions) alleles are employed ... insertion allele, compared with 20 containing exon deletions (19 tm1b and 1 CRISPR). With either group ...
  4. quinine and ATM (Dhingra et al., 2017). The specific introduction of the His95Pro mutation using CRISPR ...
  5. of the SNARE protein family. Using CRISPR/Cas9 to create a HeLa-VAMP7 knockout cell line together with knockout ... used CRISPR/Cas9 genome editing technology to generate VAMP7 knockout (KO) human HeLa cells and mouse ... editing CRISPR/Cas9 technology to generate VAMP7-knockout (KO) human HeLa cells. This genetically modified ...
  6. ... valid cellular model to study the disease, MUT gene was knocked out (KO) in HEK293 cell line by using CRISPR-CAS9 technology. Methylmalonic acid was measured in MUT-KO and wild type (WT) cells by multiple reaction ...
    Date: 1969-12-31T19:00:09-0500