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  1. ... Search for this keyword Advanced Search New Results CRISPR/Cas9 cleavages in budding yeast reveal templated insertions ... History Metrics Data Supplements Preview PDF Abstract Harnessing CRISPR-Cas9 technology has provided an unprecedented ability to ...
  2. ... binding and HEPN nuclease activation are decoupled in CRISPR-Cas13a Akshay Tambe , Alexandra East-Seletsky , View ORCID ... Info/History Metrics Data Supplements Preview PDF Abstract CRISPR-Cas13a is a CRISPR RNA (crRNA)-guided, RNA- ...
  3. ... Metrics Data Supplements Preview PDF Abstract In microbes, CRISPR-Cas systems provide adaptive immunity against invading genetic ...
  4. ... History Metrics Data Supplements Preview PDF Abstract The CRISPR-associated protein Cas9 is a widely used genome ...
  5. ... Info/History Metrics Data Supplements Preview PDF Abstract CRISPR/Cas9 systems enable many molecular activities to be ... and nicks, transcriptional activation and repression, and fluorescence. CRISPR targeting relies on base pairing of short RNA ...
  6. ... Results A universal, genome-wide guide finder for CRISPR/Cas9 targeting in microbial genomes Michelle Spoto , Elizabeth ... Metrics Data Supplements Preview PDF Abstract Background: The CRISPR/Cas system has significant potential to facilitate gene ...
  7. ... this keyword Advanced Search New Results An optimized CRISPR/Cas toolbox for efficient germline and somatic genome ... Data Supplements Preview PDF Abstract The type II CRISPR/Cas system has recently emerged as a powerful ...
  8. ... Info/History Metrics Data Supplements Preview PDF Abstract CRISPR-based genome editing is an enabling technology with ... this technology. A novel Type V, Class 2 CRISPR nuclease system was identified from Microgenomates and Smithella ...
  9. ... X-chromosome target sequences for X-shredding by CRISPR endonucleases View ORCID Profile Philippos Aris Papathanos , View ... Info/History Metrics Data Supplements Preview PDF Abstract CRISPR-based synthetic sex ratio distorters, that operate by ...
  10. ... Advanced Search New Results A versatile two-step CRISPR- and RMCE-based strategy for efficient genome engineering ... History Metrics Preview PDF Abstract The development of CRISPR/Cas9 technologies promises a quantum leap in genome- ...
  11. ... for RNA-guided gene drives based on the CRISPR nuclease Cas9 to serve as a general method ...