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  1. ... X-chromosome target sequences for X-shredding by CRISPR endonucleases View ORCID Profile Philippos Aris Papathanos , View ... Info/History Metrics Data Supplements Preview PDF Abstract CRISPR-based synthetic sex ratio distorters, that operate by ...
  2. ... investigated the in vivo function of Fank1. Methods. In this study, we generated Fank1-knockout mice using the CRISPR/Cas9 system. We then investigated the phenotype and in vivo function of Fank1. Testes and epididymis tissues ...
    Date: 1969-12-31T19:00:18-0500
  3. Features of the CRISPR-Cas system, in which bacteria integrate small segments of ... Emphasizing the population-level impact of the CRISPR-Cas system, recent experiments show that some bacteria regulate CRISPR-associated genes via the quorum sensing (QS) pathway. Here ...
  4. 2013). Furthermore, a recent genome-wide CRISPR/Cas9 screen indicated a relatively minor contribution ...
  5. palindromic repeat (CRISPR)/Cas-based RNA-guided DNA endonucleases21. TALEN and CRISPR/Cas are based on DNA ...
  6. ... PDF Abstract Clustered regularly interspaced short palindromic repeat (CRISPR) RNA-guided nucleases have gathered considerable excitement as ... we use ChIP-seq to examine genome-wide CRISPR binding specificity at gRNA-specific and gRNA-independent ...
  7. ... allows to design complex graph editing algorithms. As an example, we developed a detection algorithm for CRISPRs in a de Bruijn graph. Finally, RGFA can be used for comparing assembly graphs, e.g. to document the changes ...
    Date: 1969-12-31T19:00:22-0500
  8. quinine and ATM (Dhingra et al., 2017). The specific introduction of the His95Pro mutation using CRISPR ...
  9. Together with the recent studies of the CRISPR system ...
  10. ... affects adolescents and young adults. Here, we implement CRISPR/Cas9 genome editing and transposon-mediated somatic gene ...
  11. ... valid cellular model to study the disease, MUT gene was knocked out (KO) in HEK293 cell line by using CRISPR-CAS9 technology. Methylmalonic acid was measured in MUT-KO and wild type (WT) cells by multiple reaction ...
    Date: 1969-12-31T19:00:09-0500
  12. of control that is exerted by the mitoribosome on assembly of the OXPHOS complexes. CRISPR/Cas9 or siRNA ...
  13. as described below. Gene editing of mutated dystrophin using adeno-associated viruses (AAV) to deliver CRISPR ...
  14. ... an experimental and theoretical case study of the CRISPR-Cas immune system to contrast the behavior of ...
  15. of antibody reactivity for Huh-7 CRISPR Cas9 CD81 KO cells33 with and without CD81 addback, providing ...
  16. the microbe Acinetobacter bereziniae (UniProt accession: N8YUQ2) which was revealed to be a translated CRISPR ...
  17. ... coding variant by introducing a Mendelian SNP using CRISPR-Cas9 on distinct expression haplotypes and using the ...
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